What are the MTR and MTRR Genes? 

The MTR (methionine synthase) gene and the MTRR (methionine synthase reductase) gene both code for enzymes that are involved in the conversion of homocysteine to methionine. They are essential players in the methylation cycle. Both MTR and MTRR are vital amino acids used in the production of proteins, and proteins do most of the work in the cells in our bodies. They are responsible for the structure, function, and regulation of the body’s tissues and organs.

So, in layman’s terms, the MTR and MTRR genes are necessary for our bodies to survive and function optimally. Because MTR and MTRR are imperative to a properly functioning methylation cycle in the body, if there is a problem with either of these genes, the body will not work as it should. Some symptoms that could occur if methylation is not working properly include insomnia, depression, anxiety, allergies, IBS, muscle pain, headaches, and more. 

What is Methylation and Why It’s Important 

Methylation is a simple, yet extremely important process in the body that occurs a billion times per second and affects nearly every essential process in the body. Doesn’t sound so simple, right? Methylation helps regulate the activity of our cardiovascular, neurological, reproductive, and detox systems. 

Methylation is important to the body because it is the process that fundamentally allows the genes in our bodies to turn on and off. If you think of the body as a machine, methylation is what turns the gears. In order for the body (machine) to function at its optimal level, all of the genes (gears) need to be operating correctly — methylation controls this. 

Sometimes when a gene mutation occurs, it negatively impacts the methylation cycle. If the mutation occurs in the MTR or MTRR gene, it most definitely will affect methylation and cause a host of short-term problems, leading to chronic disease if left untreated. 

Gene Mutations in MTR and MTRR genes 

Genetic mutations occur during cell division and change the sequence of your DNA. Since your DNA sequence gives your cells the information they need to perform their functions, if part of your DNA sequence is in the wrong place, you may experience symptoms of a genetic condition. 

A gene mutation in the MTR or MTRR gene can mean that proteins in the body are negatively affected, and because proteins control so much in the body, a serious health condition may arise. MTR and MTRR are mainly responsible for your gut health, so a mutation in either of these genes can lead to various gut issues like gas, bloating, diarrhea, and more. 

How Do I Know If I Have a Gene Mutation in MTR or MTRR? 

If you are experiencing things like gut issues, poor sleep, weight gain, or problems focusing, you may have a genetic mutation. However, it is hard to tie specific symptoms to a genetic mutation because everyone’s body functions differently. A genetic test is the best and most effective way to determine if your ongoing symptoms or challenges are related to your genes and, more importantly, what you can do to fix them.

10X Health’s genetic test looks at the five genes that play an integral role in the methylation cycle in the body. We can tell from the results of your genetic test if the symptoms you are experiencing are linked to a genetic mutation in the five genes we focus on, which include the MTR and MTRR genes. We also analyze the MTHFR, COMT, and AHCY genes. 

How Complicated is the 10X Genetic Test to Complete? 

The 10X Health genetic test is very simple! All you have to do is obtain a saliva sample with the directions provided in the testing kit, put it in the provided protected container, and mail it to us. When your sample arrives at our lab, we take it from there and begin the analysis. We then provide you with a comprehensive report, along with recommendations, based on what your genes tell us. 

We also provide a personal wellness advisor who will answer your questions, check in with you throughout your wellness journey, and recommend adjustments along the way so that you reach your wellness goals. 

Knowing whether a genetic mutation is responsible for symptoms or conditions you are experiencing is knowledge that can go a long way. Your well-being may be impaired by a mutation that can be fixed with supplementation. 

Interested in learning more about 10X Health’s genetic testing? Reach out to us today! 

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